Dr Margaret Wexler
| Job Title | Contact | Location |
|---|---|---|
| Senior Lecturer & Course Manager |
M dot Wexler at uea dot ac dot uk
Tel: 3534/3633 |
Biology 1.15 |
Career
- Lecturer, University of East Anglia (2008-present)
- Senior Research Associate, University of East Anglia (1999-2009)
- Senior Research Associate, John Innes Centre (1997-1999)
- Research Assistant, University of East Anglia (1995-1996)
- Ph.D. University of Adelaide (1994)
ResearcherID
http://www.researcherid.com/rid/G-3423-2011Key Research Interests
Current Research Projects
- Microbiology and biochemistry of enhanced biological phosphorus removal.
- Molecular genetics of oestrogen degradation by activated sludge bacteria.
PhD Positions
Please email me to discuss PhD opportunities and projects within the School of Biological SciencesTeaching Activities
- Microbiology (BIO-2B28)
- Microbial biotechnology (BIO-3C09)
- Scientific Research Skills (BIO-3C40)
- Microbial and enzyme biotechnology (BIO-M101)
- Biofuels, bioremediation and bioproducts (BIO-M103)
- MSc practical (BIO-M61Y)
- Water Security – Theory and Concepts (DEV-M101)
Article
Wexler, M (2011) Microbiology and biochemistry of biological nutrient removal. Water and Sewerage (2).
Baker-Austin, C, Potrykus, J, Wexler, M, Bond, PL and Dopson, M (2010) Biofilm development in the extremely acidophilic archaeon ‘Ferroplasma acidarmanus’ Fer1. Extremophiles, 14 (6). pp. 485-491. ISSN 1431-0651
Wexler, M, Richardson, DJ and Bond, PL (2009) Radiolabelled proteomics to determine differential functioning of Accumulibacter during the anaerobic and aerobic phases of a bioreactor operating for enhanced biological phosphorus removal. Environmental Microbiology, 11 (12). pp. 3029-3044.
Wexler, M. (2009) Microbiological pollution of wastewater.
Wilmes, P, Andersson, AF, Lefsrud, MG, VerBerkmoes, NC, Wexler, M, Shah, M, Bond, PL, Hettich, RP and Banfield, JF (2008) Community proteogenomics highlights strain-variant protein expression within activated sludge performing enhanced biological phosphorus removal. The ISME Journal, 2. pp. 853-864.
Wilmes, P, Wexler, M and Bond, PL (2008) Metaproteomics provides functional insight into Activated Sludge Wastewater Treatment. PLoS One, 3 (3). p. 1778.
Baker-Austin, C, Dopson, M, Wexler, M, Sawers, RG, Stemmler, A, Rosen, BP and Bond, PL (2007) Extreme arsenic resistance by the acidophilic archaeon 'Ferroplasma acidarmanus' Fer1. Extremophiles, 11 (3). pp. 425-434.
Bond, PL and Wexler, M (2007) Metaproteomics for analysis of microbial function in the environment. Microbiology Australia, 28 (3).
Todd, JD, Rogers, R, You, GL, Wexler, Margaret, Bond, PL, Sun, L, Curson, ARJ, Malin, G, Steinke, M and Johnston, Andy (2007) Structural and regulatory genes required to make the gas dimethyl sulfide in bacteria. Science, 315 (5812). pp. 666-669.
Young, J.P.W., Crossman, L.C., Johnston, A.W.B., Thomson, N.R., Ghazoui, Z.F., Hull, K.H., Wexler, M., Curson, Aa.R.J., Todd, J.D., Poole, P.S., Mauchline, T.H., East, A.K., Quail, M.A., Churcher, C., Arrowsmith, C. and Cherevach, I. (2006) The genome of Rhizobium leguminosarum has recognizable core and accessory components. Genome Biology, 7. p. 34.
Baker-Austin, Craig, Dopson, M., Wexler, M., Sawers, R.G. and Bond, Philip (2005) Molecular insight into extreme copper resistance in the extremophilic archaeon "Ferroplasma acidarmanus" Fer1. Microbiology, 151. pp. 2637-2646.
Diaz-Mireles, E., Wexler, M., Todd, J.D., Bellini, D., Johnston, A.W.B. and Sawers, R.G. (2005) The manganese-responsie repressor Mur of Rhizobium leguminosarum is a member of the Fur-superfamily that recognizes and unusual operator sequence. Microbiology, 151. pp. 4071-4078.
Li, Y., Wexler, M., Richardson, D.J., Bond, P.L. and Johnston, A.W.B. (2005) Screening a wide host-range, waste-water metagenomic library in tryptophan auxotrophs of Rhizobium leguminosarum and of Escherichia coli reveals different classes of cloned trp genes. Environmental Microbiology, 7. pp. 1927-1936.
Wexler, M., Bond, P.L., Richardson, D.J. and Johnston, A.W.B. (2005) A wide host-range metagenomic library from a waste water treatment plant yields a novel alcohol/aldehyde dehydrogenase that allows Rhizobium leguminosarum but not Escherichia coli to grow on ethanol. Environmental Microbioloy, 7 (12). pp. 1917-1926. ISSN 1462-2912
Diaz-Mireles, E., Wexler, M., Sawers, G., Bellini, D., Todd, J.D. and Johnston, A.W.B. (2004) The Fur-like protein Mur of Rhizobium leguminosarum is a Mn2+ responsive transcriptional regulator. Microbiology, 150. pp. 1447-1456.
Todd, J.D., Wexler, M., Sawers, G., Yeoman, K.H., Poole, P.S. and Johnston, A.W.B. (2003) RirA, an iron-responsive regulator in the symbiotic bacterium Rhizobium leguminosarum. Microbiology, 148. pp. 4059-4071.
Wexler, M., Todd, J.D., Kolade, O., Bellini, D., Hemmings, A.M., Sawers, G. and Johnston, A.W.B. (2003) Fur is not the global regulator of iron uptake genes in Rhizobium leguminosarum. Microbiology, 149. pp. 1357-1365.
Buchanan, G., de Leeuw, E., Stanley, N.R., Wexler, M., Berks, B.C., Sargent, F. and Palmer, T. (2002) Functional complexity of the twin-arginine translocase TatC component revealed by site-directed mutagenesis. Molecular Microbiology, 43. pp. 1457-1470.
Carter, R.A., Worsley, P.S., Sawers, G., Challis, G.L., Dilworth, M.J., Carson, K.C., Lawrence, J.A., Wexler, M., Johnston, A.W.B. and Yeoman, K.H. (2002) The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: their expression in other genera requires ECF s factor Rpol. Molecular Microbiology, 44 (5). pp. 1153-1166. ISSN 0950-382X
Kolade, O.O., Bellini, P., Wexler, M., Johnston, A.W.B., Grossmann, J.G. and Hemmings, A.M. (2002) Structural studies of the Fur protein from Rhizobium leguminosarum. Biochemical Society Transactions, 30. pp. 771-774.
Johnston, A.W.B., Yeoman, K.H. and Wexler, M. (2001) Metals and the rhizobial-legume symbiosis - Uptake, utilization and signalling. Advances in Microbial Physiology, 45. pp. 113-156.
Wexler, M., Yeoman, K.H., Stevens, J.B., de Luca, N.G., Sawers, G and Johnston, A.W.B. (2001) The Rhizobium leguminosarum tonB gene is required for the uptake of siderophore and haem as sources of iron. Molecular Microbiology, 41 (4). pp. 1-17. ISSN 0950-382X
Wexler, M., Sargent, F., Jack, R.L., Stanley, N.R., Bogsch, E.G., Robinson, C., Berks, B.C. and Palmer, T. (2000) TatD is a cytoplasmic protein with Dnase activity - No requirement for TatD family proteins in Sec-independent protein export. Journal of Biological Chemistry, 275. pp. 16717-16722.
Book Section
Wexler, M, Bond, PL, Richardson, DJ and Johnston, AWB (2011) Functional screening of a wide host-range metagenomic library from a wastewater treatment plant yields a novel alcohol/aldehyde dehydrogease. In: Metagenomics and Different Habitats Handbook of Molecular Microbial Ecology. Wiley-Blackwell. ISBN 978-0-470-64719-6
External Activities and Indicators of Esteem
- Member of the Society for General Microbiology and International Society for Microbial Ecology
Administrative Posts/Responsibilities
- Module organiser for Microbial biotechnology (BIO-3C09)
- Module organiser for MSc practical Class (BIO-M61Y)
- Module organiser for Biofuels, Bioremediation and Bioproducts (BIO-M103)
- Chair of Staff Student Liaison Group
- Member of exam board (MSc Biotechnology for a Sustainable Future and MSc Molecular Medicine)
- Member of BIO Teaching Executive


