Article

Banos-Sanz, JI, Sanz-Aparicio, J, Brearley, CA and Gonzalez, B (2012) Expression, purification, crystallization and preliminary X-ray diffraction analysis of the apo form of Ins5 2-K from Arabidopsis thaliana. Acta Crystallographica Section F, 68. pp. 701-704.

Banoz-Sanz, JI, Sanz-Aparicio, J, Whitfield, H, Hamilton, C, Brearley, CA and Gonzalez, B (2012) Conformational changes undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-lobe and Enantiomeric Substrate Preference. The Journal of Biological Chemistry. (In Press)

Hanke, DE, Parmar, PN, Caddick, SEK, Green, P and Brearley, CA (2012) Synthesis of inositol phosphate ligands of plant hormone receptor complexes: pathways of inositol hexakisphosphate turnover. Biochemical Journal, 444 (3). pp. 601-609. ISSN 0264-6021

Ignacio, J, S-Aparicio, J, Whitfield, H, Hamilton, C, Brearley, C and Gonzalez, B (2012) Conformational changes undergone by AtlP5 2-K upon substrate binding: The role of N-lobe and enantiomeric substrate preference. The Journal of Biological Chemistry. (In Press)

Lee, B-R, Huseby, S, Koprivova, A, Chetelat, A, Wirtz, M, Mugford, ST, Navid, E, Brearley, CA, Saha, S, Mithen, R, Hell, R, Farmer, EE and Kopriva, S (2012) Effects of fou8/fry1 mutation on sulfur metabolism. Is decreased internal sulfate the trigger of sulfate starvation response? PLoS One (PONE-D-12-01548R2).

Estavillo, GM, Crisp, PA, Pornsiriwong, W, Wirtz, M, Collinge, D, Carrie, C, Giraud, E, Whelan, J, David, P, Javot, H, Brearley, C, Hell, R, Marin, E and Pogson, BJ (2011) Evidence for a SAL1-PAP Chloroplast Retrograde Pathway That Functions in Drought and High Light Signaling in Arabidopsis. The Plant Cell Online, 23 (11). pp. 3992-4012. ISSN 1040-4651

Panzeri, D, Cassani, E, Doria, E, Tagliabue, G, Forti, L, Campion, B, Bollini, R, Brearley, CA, Pilu, R, Nielsen, E and Sparvoli, F (2011) A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity. New Phytologist. no-no. ISSN 0028646X

Seipke, RF, Barke, J, Brearley, C, Hill, L, Yu, DW, Goss, RJM and Hutchings, MI (2011) A Single Streptomyces Symbiont Makes Multiple Antifungals to Support the Fungus Farming Ant Acromyrmex octospinosus. PLoS ONE, 6 (8). e22028. ISSN 1932-6203

Gonzalez, B, Banos-Sanza, JI, Villatea, M, Brearley, CA and Sanz-Aparicio, J (2010) Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition. Proceedings of the National Academy of Sciences, 107 (21). pp. 9608-9613.

Robson, F, Okamoto, H, Patrick, E, Harris, S-R, Wasternack, C, Brearley, CA and Turner, JG (2010) Jasmonate and Phytochrome - A signaling in Arabidopsis wound and shade responses are integrated through JAZ1 stability. Plant Cell, 22 (4). pp. 1143-1160.

Guymer, D, Maillard, J, Agacan, MF, Brearley, C and Sargent, F (2010) Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping. FEBS Journal, 277 (2). pp. 511-525. ISSN 1742464X

Baños-Sanz, JI, Villate, M, Sanz-Aparicio, J, Brearley, C and González, B (2010) Crystallization and preliminary X-ray diffraction analysis of inositol 1,3,4,5,6-pentakisphosphate kinase from Arabidopsis thaliana. Acta Crystallographica Section F Structural Biology and Crystallization Communications, 66 (1). pp. 102-106. ISSN 1744-3091

Todd, J, Curson, A, Nikolaidou-Katsaraidou, N, Brearley, C, Watmough, N, Chan, Y, Bulman Page, P, Sun, L and Johnston, AWB (2010) Molecular dissection of bacterial acrylate catabolism - unexpected links with dimethylsulfoniopropionate catabolism and dimethyl sulfide production. Environmental Microbiology, 12 (2). pp. 327-343.

Nagy, R, Grob, H, Weder, B, Green, P, Klein, M, Frelet, A, Schjoerring, JK, Brearley, CA and Martinoia, E (2009) The Arabidopsis ATP-binding cassette protein ATMRP5/ATABCC5 is a high-affinity inositol hexakisphosphate transporter involved in guard cell signaling and phytate storage. Journal of Biological Chemistry, 284. pp. 33614-33622.

Tedman-Jones, JD, Lei, R, Jay, F, Fabro, G, Li, X, Reiter, WD, Brearley, C and Jones, JD (2008) Characterization of Arabidopsis mur3 mutations that result in constitutive activation of defence in petioles, but not leaves. Plant Journal, 56 (5). pp. 691-703.

Murphy, A, Otto, B, Brearley, C, Carr, J and Hanke, D (2008) A role for inositol hexakisphosphate in the maintenance of basal resistance to plant pathogens. Plant Journal, 56 (4). pp. 638-652.

Brearley, CA (2008) Sorting out Ptdlns(4,5)P2 and clathrin coated vesicles in plants. Biochemical Journal, 415 (3). pp. 1-3. ISSN 0264-6021

Caddick, SE, Harrison, CJ, Stavridou, I, Mitchell, JL, Hemmings, AM and Brearley, CA (2008) Solanum tuberosum inositol phosphate kinase (StlTPK1) displaying inositol phosphate-inositol phosphate and inositol phosphate-ADP phosphotransferase activities. FEBS Letters, 582 (12). pp. 1731-1737.

Curson, ARJ, Rogers, R, Todd, JD, Brearley, CA and Johnston, AWB (2008) Molecular genetic analysis of a dimethylsulfoniopropionate lyase that liberates the climate-changing gas dimethylsulfide in several marine a-proteobacteria and Rhodobacter sphaeroides. Environmental Microbiology, 10 (3). pp. 757-767.

Sweetman, D, Stavridou, I, Johnson, S, Green, P, Caddick, SE and Brearley, CA (2007) Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis. FEBS Letters, 581 (22). pp. 4165-4171.

Caddick, SE, Harrison, CJ, Stavridou, I, Johnson, S and Brearley, CA (2007) A lysine accumulation phenotype of Sclpk2Delta mutant yeast is rescued by Solanum tuberosum inositol phosphate multikinase. Biochemical Journal, 403. pp. 381-389. ISSN 0264-6021

Harrison, CJ, Caddick, SEK, Stavridou, I, Johnson, S and Brearley, C (2007) A lysine accumulation phenotype of ScIpk2Δ mutant yeast is rescued by Solanum tuberosum inositol phosphate multikinase. Biochemical Journal, 403 (3). pp. 381-389. ISSN 02646021

Casaravilla, C, Brearley, C, Soule, S, Fontana, C, Veiga, N, Beisso, M, Ferreira, F, Kremer, C and Diaz, A (2006) Characterisation of myo-inositol hexakisphosphate deposits from larval Echinococcus granulosus. FEBS Journal, 273 (14). pp. 3192-3203.

Sweetman, D, Johnson, S, Caddick, SEK, Hanke, DE and Brearley, CA (2006) Characterization of an Arabidopsis inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Atlpk1). Biochemical Journal, 394 (1). pp. 95-103. ISSN 0264-6021

Lin, W-H, Wang, Y, Mueller-Roeber, B, Brearley, CA, Xu, ZH and Xue, H-W (2005) At5PTase 13 Modulates Cotyledon Vein Development through Regulating Auxin Homeostasis. Plant Physiology, 139 (4). pp. 1677-1691.

Gomez-Merino, FC, Trejo-Telez, LI, Skiryczl, A, Brearley, CA, Dormann, P and Mueller-Roeber, B (2005) Arabidopsis ATDGK7, the smallest member of plant diacylglycerol kinases, unique biochemical features and saturates at low substrate. Journal of Biological Chemistry, 280. pp. 34888-34899.

Fung, CYE, Brearley, CA, Farndale, RW and Mahaut-Smith, MR (2005) A major role for P2X(I) receptors in the early collagen-evoked intracellular Ca2+ responses of human platelets. Thrombosis and Haemostasis, 94 (1). pp. 37-40.

Xu, J, Brearley, CA, Lin, W-H, Wang, Y, Ye, R, Mueller-Roeber, B, Xu, Z-H and Xue, H-W (2005) A role of Arabidopsis inositol polyphosphate kinase, AtlPK2{alpha}, in pollen germination and root growth. Plant Physiology, 137 (1). pp. 94-103.

Gomez-Merino, FC, Brearley, CA, Ornatowska, M, Abdel-Haliem, ME, Zanor, MI and Mueller-Roeber, B (2004) AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol, and exhibits cold-inducible gene expression. Journal of Biological Chemistry, 279. pp. 8230-8241.

Lemtiri-Chlieh, F, MacRobbie, EA, Webb, AA, Manison, NF, Brownlee, C, Skepper, JN, Chen, J, Prestwich, GD and Brearley, CA (2003) Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells. Proceedings of the National Academy of Sciences USA, 100 (17). pp. 10091-10095. ISSN 10091-10095

Xia, HJ, Brearley, C, Elge, S, Kaplan, B, Fromm, H and Mueller-Roeber, B (2003) Arabidopsis inositol polyphosphate 6-/3-kinase is a nuclear protein that complements a yeast mutant lacking a functional ArgR-Mcm1 transcription complex. Plant Cell, 15 (2). pp. 449-463.

Xiao, S, Brown, S, Patrick, E, Brearley, C and Turner, JG (2003) Enhanced transcription of the Arabidopsis disease resistance genes RPW8.1 and RPW8.2 via a salicylic acid-dependent amplification circuit is required for hypersensitive cell death. Plant Cell, 15 (1). pp. 33-45. ISSN 1040-4651

Elge, S, Brearley, C, Xia, HJ, Kehr, J, Xue, HW and Moeller Roeber, B (2001) An Arabidopsis inositol phospholipid kinase strongly expressed in procambial cells: Synthesis of Ptdlns(4,5)P-2 and Ptdlns(3,4,5)P-3 in insect cells by 5-phosphorylation of precursors. The Plant Journal, 26 (6). pp. 561-571. ISSN 0960-7412

Rolf, MG, Brearley, CA and Mahaut-Smith, MP (2001) Platelet shape change evoked by selective activation of P2X(1) purinoceptors with alpha, beta-methylene ATP. Thrombosis and Haemostasis, 85. pp. 303-308.

Patent

WO2001GB03008 20010704 (2002) Measurements of Inositol Phospholipid Mass. .