The Microbial Pathogen Biology group has research interests in:
- Viruses, especially understanding how viruses subvert cytoskeletal and membrane trafficking pathways during replication, assembly and egress from cells
- Trypanosomes, especially the role of microtubules and lipid rafts during cell invasion and intracellular trafficking, and the mechanisms of iron uptake via host transferrin
- Adaptation of Helicobacter to cellular and environmental influences
- Technology development, especially target identification for new drugs and diagnostics for protozoan parasites
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Dr Tom Wileman Cellular sites of virus replication and assembly . Use of cytoskeleton for virus movement in cells. Effects of viruses on secretion . |
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Dr Dietmar Steverding iron metabolism of bloodstream forms of Trypanosoma brucei drug development against protozoan parasites PCR diagnosis of sleeping sickness |
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Dr Kevin Tyler Cellular Microbiology: How do our cells respond to invasion by protozoan parasites? Eukaryotic Microbiology: How does the cell biology of protozoan parasites vary from our own? Diagnostics and Therapeutics: How can we usefully apply such knowledge? |
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Dr Ian Beales Pathophysiology of gastrointestinal peptides in inflammation and cancer Pathogenesis and novel therapies for Barrett’s oesophagus Regulation of gastrointestinal function by adipocytokines |
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Dr Penny Powell NF-kappaB and interferon responses to viral infection Identification of viral proteins that block interferon production and isolation of the host proteins Flaviviruses which cause hemorrhagic diseases through infection of vascular endothelial cells |
