Prof John Saxton
| Job Title | Contact | Location |
|---|---|---|
| Professor of Clin. Exercise Physiology |
John dot Saxton at uea dot ac dot uk
Tel: +44 (0)1603 59 3098 |
Queens Building 2.08 |
Biography
Further publications
Invited review papers
Tew GA, Saxton JM, Hodges GJ (2012). Exercise training and the control of skin blood flow in older adults. J Nutr Health Aging 16, 237-241.
Saxton JM (2006). Diet, physical activity and energy balance and their impact on breast and prostate cancers. Nutrition Research Reviews 19, 197-215.
Invited book Chapters
Brouke L, Saxton JM (2011). Colorectal, breast and prostate cancer. In Exercise and chronic disease: an evidence-based approach (Edited by Saxton JM). Routledge, Oxon 2011, pp 364-380.
Saxton JM (2010). Exercise and cancer mortality. In Exercise and cancer survivorship: impact on health outcomes and quality of life (Edited by Saxton JM & Daley AJ). Springer, New York, pp 189-210.
Saxton JM (2006). Special populations:Testing older people. In: Sport and Exercise Physiology Testing Guidelines: Volume 1: Sport Testing. Edited by Winter EM, Jones AM, Davidson R, Bromley P, Mercer T. Taylor & Francis, Oxford, Chapter 39, pp 334-346.
Saxton JM, Cable T. (2006). Clinical Exercise physiology: Peripheral circulatory disorders. In: Sport and Exercise Physiology Testing Guidelines: Volume 2: Exercise and Clinical Testing. Edited by Winter EM, Jones AM, Davidson R, Bromley P, Mercer T. Taylor & Francis, Oxford, Chapter 18, pp 169-178.
Saxton JM (2006). Special populations: Testing older people. In: Sport and Exercise Physiology Testing Guidelines: Volume 2: Exercise and Clinical Testing. Edited by Winter EM, Jones AM, Davidson R, Bromley P, Mercer T. Taylor & Francis, Oxford, Chapter 23, pp 224-236.
Saxton JM (2005). Leucocyte adhesion molecule expression in health and cardiovascular disease: what is the significance of changes induced by acute bouts of exercise? In: Trends in Exercise and Health Research. Edited by Swan RL. Nova Science Publishers, Inc., New York, USA. pp 187-221.
Saxton JM (2000). Acute and chronic health effects of hand-arm vibration. In: Legislation for noise and vibration: enforcement, compliance, and benefits. ImechE Seminar Publication, pp 7-10. Professional Engineering Publishing, London.
Book Editorship
Saxton JM, Daley AJ (2010). Exercise and cancer survivorship: impact on health outcomes and quality of life (Edited by Saxton JM, Daley AJ). Springer, New York.
This book explores the impact of physically active lifestyle on health outcomes that are highly relevant to cancer patients at all stages of the cancer experience. Twelve active and eminent researchers or research groups in this field from the USA, Canada and Europe present an up-to-date synthesis of the scientific evidence.
Saxton JM (2011). Exercise and chronic disease: an evidence-based approach (Edited by Saxton JM). Routledge, Oxford.
Drawing on data from randomised controlled trials and observational evidence, and written by a team of international researchers and medical and health practitioners, the book explores the evidence across a wide range of chronic diseases. Each chapter addresses the frequency, intensity, duration and modality of exercise that could be employed as an intervention for each condition and, importantly, assesses the impact of those interventions on important health outcomes for patients.Career
John Saxton graduated from Loughborough University in 1990 before embarking upon PhD research in skeletal muscle physiology at the University of Wolverhampton and University of Massachusetts at Amherst, USA . Following a period of post-doctoral work, he undertook lectureships at Oxford Brookes University and the University of Sheffield, before working as a research physiologist in Health and Safety Executive research laboratories in Sheffield. He then spent 10 years at Sheffield Hallam University, where he led the Active Health Research Group and was Principal Investigator for several randomised controlled exercise trials with clinical populations, including cardiovascular disease and cancer patients. In March 2010, he was appointed to the position of Professor of Clinical Exercise Physiology at UEA.
Academic Background
Academic Appointments
Mar 2010
Professor of Clinical Exercise Physiology, School of Allied Health Professions, University of East Anglia, Norwich NR4 7TJ
Mar 2010
Honorary Visiting Research Fellow, Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield S10 2BP
Jul 2006 - Mar 2010
Reader in Clinical Exercise Physiology. Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield S10 2BP
Mar 2004 - Jul 2006
Principal Research Fellow (Exercise Physiology), Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield S10 2BP
Feb 2000 - Feb 2004
Senior Research Fellow (Exercise Physiology), Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield S10 2BP
Jan 1999- Feb 2000
Senior Research Physiologist, Health and Safety Laboratory, Broad Lane, Sheffield S37HQ
Dec 1995 - Jan 1999
Lecturer B, Institute of Sports Medicine and Exercise Science, University of Sheffield, 23 Claremont Crescent, Sheffield S10 2TA
Oct 1994 - Dec 1995
Lecturer, School of Biological and Molecular Sciences, Oxford Brookes University, Gipsy Lane Campus, Headington, Oxford OX3 OBP
Key Research Interests
Professor Saxton’s research is focused on the role of exercise and other lifestyle factors in the prevention and management of age-related chronic conditions. Specific research questions that his research aims to address include: how can we optimise exercise therapy (frequency, intensity, time and type) to bring the greatest health or therapeutic benefits? In those with long-term conditions, what is the role of exercise in disease modification? Why do some patients respond/adapt differently to exercise training? What are the contra-indications to exercise in different clinical groups? He has worked with several clinical populations, including cancer patients and survivors, patients with peripheral vascular disease, chronic heart failure and multiple sclerosis. As Principal Investigator or Co-Investigator, his research has been supported by the British Heart Foundation, Heart Research UK, Cancer Research UK, the American Institute for Cancer Research, the Health and Safety Executive, the Food Standards Agency and the Multiple Sclerosis Society.
In 2010, he was the lead editor of a book entitled “Exercise and cancer survivorship: impact on health outcomes and quality of life”, published by Springer Scientific, New York and in 2011 was the sole editor of a second book entitled “Exercise and chronic disease: an evidence-based approach”, published by Routledge, UK. His published clinical intervention studies have helped to build a solid evidence-base to support the use of exercise in the management of many age-related long-term conditions.
Research Grants/Funding
Funded research projects
UK Multiple Sclerosis Society (March 2009 – March 2012): The effects of a pragmatic exercise therapy intervention on physical activity and important health outcomes influencing maintenance in people with multiple sclerosis (Principal Investigator). The major aim of this study was to investigate whether a pragmatic exercise intervention is effective for evoking improvements in physical activity behaviour and, as a consequence, health outcomes likely to influence maintenance in people with multiple sclerosis. This was a collaboration between Sheffield Hallam University, the Academic Neurology Unit at the Royal Hallamshire Hospital and the University of Birmingham.
American Institute for Cancer Research (February 2006 – February 2009): The effect of a lifestyle intervention on body weight, psychological health status and risk factors associated with disease recurrence in women recovering from breast cancer treatment (Principal Investigator). The major aim of this study was to investigate the effects of a practical lifestyle intervention for overweight or obese women (BMI > 25) who had undergone breast cancer treatment, on body weight, indices of psychological well-being, biomarkers associated with disease recurrence and physiological health status and quality of life. This was a collaboration between Sheffield Hallam University, University of Sheffield at the Weston Park Hospital and the Universities of Birmingham and Glasgow.
Heart Research UK (July 2006 – July 2010): Testosterone as an adjunct to exercise rehabilitation: effects on exercise capacity, inflammatory markers and quality of life in hypogonadal males with chronic heart failure (Principal Investigator). The major aim of this study was to examine the effects of testosterone therapy, as an adjunct to exercise rehabilitation, on functional fitness, skeletal muscle/cardiac function, circulating inflammatory mediators and disease-specific quality of life in hypogonadal males with chronic heart failure. This was a collaboration between Sheffield Hallam University and the Department of Cardiology, University of Sheffield at the Royal Hallamshire Hospital.
Food Standards Agency (October 2005 – October 2008): Effect of a dietary intervention on functional immune status in the elderly (Co-Investigator). The major aim of this study was to investigate the effects of a food-based intervention and micronutrient supplement intervention on the functioning of circulating immune cells in the elderly.
British Heart Foundation (November 2005 – May 2006): The effects of upper- and lower-limb exercise training on biomarkers of atherosclerosis and cardiovascular risk in intermittent claudication (Principal Investigator). The major aim of this study was to investigate the effects of different exercise training programmes on circulating soluble adhesion molecules and inflammatory markers in patients with peripheral vascular disease. This was a collaboration between Sheffield Hallam University, the Sheffield Vascular Institute, Northern General Hospital and the School of Medicine and Biomedical Sciences at the University of Sheffield.
Cancer Research UK (October 2002 - October 2005): The effects of exercise therapy upon quality of life in female breast cancer survivors ((Co-Investigator). The major aim of this study was to examine the effects of exercise therapy on measures of physical fitness, psychological well-being and quality of life in breast cancer survivors. This was a collaboration between Sheffield Hallam University, Weston Park Hospital and Glasgow University.
British Heart Foundation (September 2000 - September 2004): A comparison of upper limb and lower limb exercise training in patients with intermittent claudication (Co-Investigator). The major aim of this study was to compare the effects of different exercise training programmes on symptomatic improvements and quality of life in patients with peripheral vascular disease. This was a collaboration between Sheffield Hallam University, the Sheffield Vascular Institute, Northern General Hospital and the School of Medicine and Biomedical Sciences at the University of Sheffield.
Health and Safety Executive (September 2002 - September 2004): The effects of extreme thermal environments on the risks associated with manual handling tasks (Principal Investigator). The major aim of this study was to examine the effects of adverse environmental conditions (high heat, high humidity, and cold) on physiological responses and the health & safety risks arising from performance of whole-body manual handling tasks. This was a collaboration between Sheffield Hallam University and the Health & Safety Laboratory, an agency of the Health & Safety Executive.
Consensus Meetings and Expert Panels
- Breast Cancer Campaign Research Gap Analysis 2012. Invited expert for the Breast Cancer Prevention Working Group. Breast Cancer Campaign Head Office, Clinton Street, London, October 31, 2012.
- Multiple Sclerosis International Federation Consensus Meeting 2012 (Invited expert): Core outcome measures for exercise studies in multiple sclerosis. University of Glasgow, February 14-15, 2012.
- UK Physical Activity Guidelines Consensus Meeting (invited expert): Coordinated and funded by representatives from the Departments of Health in the home country Governments and the British Heart Foundation National Centre on Physical Activity and Health. Crown Plaza Hotel, Marlow, Buckinghamshire, October 21-22, 2009.
- 'Physical activity in the prevention of cancer'. British Association of Sport and Exercise Sciences Consensus Statement Conference: Physical Activity in the Prevention of Chronic Disease (invited presenter and Expert Panel member). Brunel University, Middlesex, April 24, 2007.
Teaching Interests
Professor Saxton has extensive teaching experience at undergraduate and postgraduate level and has a strong commitment to people development, including the nurturing of up and coming researchers. He has supervised seven PhD students to completion and is currently supervising five PhD students, two at Sheffield Hallam University and three at the University of East Anglia.
Undergraduate and postgraduate teaching experience
Oxford Brookes University
At Oxford Brookes University, he taught on the undergraduate degree programmes in Sport and Exercise Science and Nursing. Lectures and practical sessions focused on fundamental human physiology topics and the physiological responses to acute and chronic exercise.
University of Sheffield
At the University of Sheffield, he was module leader for the ‘Physiology of Exercise’ and ‘Introductory Biomechanics’ modules of the Master’s level course in Sport and Exercise Science. The ‘Physiology of Exercise’ module included lectures and practical workshops on the musculoskeletal & neuromuscular system, cardiopulmonary function and performance, high intensity exercise, and immune responses to exercise.
Sheffield Hallam University
At Sheffield Hallam University, he was module leader for the ‘Physical Activity in Disease Prevention and Rehabilitation’ module of the MSc course in Physical Activity for Health that was launched in September 2003. He had a major role in the design of this module, which covered the pathophysiology of chronic disease conditions and evidence for the impact of appropriately designed physical activity programmes on risk reduction and alleviation of symptoms/improvements in quality of life. This module was closely aligned with the programme of clinical exercise science research being undertaken. He also delivered skeletal muscle physiology and peripheral arterial disease lectures on the M.Sc. in Sport and Exercise Science course and was involved in the supervision of postgraduate level projects at Sheffield Hallam University and the University of Sheffield.
University of East Anglia
At the University of East Anglia, he lectures to undergraduate and pre-registration Masters students of Physiotherapy within the School of Allied Health Professions. These lectures cover clinical exercise physiology topics and skeletal muscle physiology. In addition, he is frequently invited to lecture to undergraduate and Masters level students, and to research groups at University departments around the UK and internationally.
PhD Supervision
Professor Saxton’s research portfolio encompasses projects that are focused on the role of exercise and other lifestyle factors in the prevention and management of age-related chronic conditions. PhD programmes aim to address specific research questions, such as:
What is the role of exercise in ameliorating the risk of age-related chronic conditions, including cancer?
How can exercise therapy be optimised (frequency, intensity, time and type) to bring the greatest health and therapeutic benefits for those with age-related chronic conditions and cancer?
What is the role of exercise in primary or secondary disease risk modification?
Why do some patients respond/adapt differently to exercise training?
What are the contra-indications to exercise in different clinical groups?
Projects involve several clinical populations, including cancer patients and survivors, patients with peripheral vascular disease, chronic heart failure and multiple sclerosis.
PhD completions
- Irena Zwierska: A comparison of upper-limb and lower-limb exercise training in elderly patients with intermittent claudication. Director of Studies. PhD awarded 2005 by Sheffield Hallam University.
- Andrew Davies: The effects of extreme thermal environments on the risks associated with manual handling tasks. Director of Studies. PhD awarded 2006 by Sheffield Hallam University.
- Stephen Hodgson: Proximal humerus fracture rehabilitation in the elderly. Co-Supervisor. PhD awarded 2006 by Sheffield Hallam University.
- Helen Crank: The effects of exercise therapy upon quality of life in female breast cancer survivors. Co-Supervisor. PhD awarded 2007 by Sheffield Hallam University.
- Borja Sanudo Corrales: Comparative effect of two exercise programs on quality of life and functional ability in women with fibromyalgia: a randomized controlled trial. Co-Supervisor. PhD awarded 2009 by University of Seville, Spain.
- Garry Tew: Physiological effects of exercise training in elderly patients with peripheral vascular disease. Director of Studies. PhD awarded 2009 by Sheffield Hallam University.
- Liam Bourke: The effects of a lifestyle intervention on health outcomes in elderly prostate and colorectal cancer patients. Director of Studies. PhD awarded 2010 by Sheffield Hallam University.
MD completion
- Shah Nawaz: Exercise studies in intermittent claudication. Co-Supervisor. Doctor of Medicine awarded 2001 by the University of Sheffield.
Current PhD supervision at Sheffield Hallam University
- Martin Stout: Testosterone as an adjunct to exercise rehabilitation: effects on exercise capacity, inflammatory markers and quality of life in elderly hypogonadal males with chronic heart failure. Director of Studies. July 2007 –
- Anouska Carter: The effects of a pragmatic exercise therapy intervention on physical activity and important health outcomes influencing maintenance in people with multiple sclerosis. Director of Studies. January 2009-
Current PhD supervision at the University of East Anglia
- Liane Lewis: Self-determination theory as a model for evoking sustained changes in physical activity behaviour in men and women enrolled on the NHS Bowel Screening Programme in Norfolk. Director of Studies. October 2011 –
- Barnabus Shaw: The effects of a pragmatic exercise intervention on bowel health in men and women enrolled on the NHS Bowel Screening Programme in Norfolk: studies of epigenetic markers in colon epithelial tissue, leukocytes and buccal cells. Director of Studies. October 2011 –
- Kelly Semper: A qualitative analysis of the perceived health benefits resulting from engaging in a physical activity intervention following bowel cancer screening in Norfolk. Director of Studies. October 2011 –
Current MD supervision at the University of East Anglia
- Srijit Banerjee: Preoperative Exercise Protocol to Aid Recovery (PREPARE) after Radical Cystectomy. Director of Studies. July 2012 –
- Wilphard Ndjavera: Should Urologists assess cardiovascular risk of Androgen Deprivation Therapy (ADT) in prostate cancer patients and can exercise therapy improve outcomes? Director of Studies. September 2012 –
Article
Saxton, John, Carter, A, Daley, A.J, Snowdon, N, Woodroofe, M.N, Petty, J, Roalfe, A, Tosh, J and Sharrack, B (2013) Pragmatic exercise intervention for people with multiple sclerosis (ExIMS Trial): Study protocol for a randomised controlled trial. Contemporary Clinical Trials, 34 (2). pp. 205-211. ISSN 1551-7144 (In Press)
Scott, E, Daley, A.J, Doll, H, Woodroofe, N, Coleman, R.E, Mutrie, N, Crank, H, Powers, H.J and Saxton, John (2013) Effects of an exercise and hypocaloric healthy eating program on biomarkers associated with long-term prognosis after early stage breast cancer: a randomized controlled trial. Cancer Causes & Control, 24 (1). pp. 181-191. ISSN 0957-5243
Stout, M, Tew, G.A, Doll, H, Zwierska, I, Woodroofe, N, Channer, K.S and Saxton, John (2012) Testosterone therapy during exercise rehabilitation in male patients with chronic heart failure who have low testosterone status: a double-blind randomized controlled feasibility study. American Heart Journal, 164 (6). pp. 893-901.
Bourke, Liam, Sohanpal, Ratna, Nanton, Veronica, Crank, Helen, Rosario, Derek J and Saxton, John (2012) A quality study evaluating experiences of a lifestyle intervention in men with prostate cancer undergoing androgen suppression therapy. Trials, 13 (208).
Forster, S.E, Powers, H.J, Foulds , G.A, Hopkinson, K, Parker, S.G, Young, T.A, Saxton, John, Pockley, A.G and Williams, E.A (2012) Improvement in nutritional status reduces the clinical impact of infections in older adults. Journal of the American Geriatric Society, 60 (9). pp. 1645-1654. ISSN 1532-5415
Tew, G.A, Saxton, John and Hodges, G.J (2012) Exercise training and the control of skin blood flow in older adults. The Journal of Nutriton, Health and Aging, 16 (3). pp. 237-41. ISSN 1279-7707
Saxton, JM, Zwierska, I, Blagojevic, M, Choksy, SA, Nawaz, S and Pockley, AG (2011) Upper- versus lower-limb aerobic exercise training on health-related quality of life in patients with symptomatic peripheral arterial disease. Journal of Vascular Surgery, 53 (5). pp. 1265-1273.
Tew, Garry Alan, Saxton, John M, Klonizakis, Markos, Moss, James, Ruddock, Alan Dean and Hodges, Gary J (2011) Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating. Journal of applied physiology (Bethesda, Md. : 1985), 110 (5). pp. 1264-1270. ISSN 1522-1601
Saxton, J, Zwierska, I, Blagojevic, M, Choksy, SA, Nawaz, S and Pockley, AG (2011) Upper-versus lower-limb aerobic exercise training on health-related quality of life in patients with symptomatic peripheral arterial disease. Journal of Vascular Surgery, 53 (5). pp. 1265-1273.
Bourke, L, Thompson, G, Gibson, DJ, Daley, A, Crank, H, Adam, I, Shorthouse, A and Saxton, JM (2011) Pragmatic lifestyle intervention in patients recovering from colon cancer: a randomized controlled pilot study. Archives of physical medicine and rehabilitation, 92 (5). pp. 749-55. ISSN 1532-821X
Bourke, Liam, Doll, Helen, Crank, Helen, Daley, Amanda, Rosario, Derek and Saxton, John M (2011) Lifestyle intervention in men with advanced prostate cancer receiving androgen suppression therapy: a feasibility study. Cancer Epidemiology, Biomarkers & Prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 20 (4). pp. 647-57. ISSN 1538-7755
Tew, Garry A, Klonizakis, Markos, Moss, James, Ruddock, Alan D, Saxton, John M and Hodges, Gary J (2011) Reproducibility of cutaneous thermal hyperaemia assessed by laser Doppler flowmetry in young and older adults. Microvascular research, 81 (2). pp. 177-82. ISSN 1095-9319
Sanudo, B, Galiano, D, Carrasco, L, Bragojevic, M, de Hoyo, M and Saxton, JM (2010) Aerobic exercise versus combined exercise therapy in women with fibromyalgia syndrome: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation, 91 (12). pp. 1838-1843.
Tew, GA, Ruddock, A and Saxton, JM (2010) Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise. Eur J Appl Physiol, 110 (5). pp. 1083-1089.
Bourke, Liam, Tew, Garry A, Milo, Marta, Crossman, DC, Saxton, JM and Chico, Timothy JA (2010) Study protocol: a randomised controlled trial investigating the effect of exercise training on peripheral blood gene expression in patients with stable angina. BMC Public Health, 10 (1). p. 620. ISSN 1471-2458
Forster, SE, Jones, L, Saxton, J, Flower, DJ, Foulds, G, Powers, HJ, Parker, SG, Pockley, AG and Williams, EA (2010) Recruiting older people to a randomised controlled dietary intervention trial - how hard can it be? BMC Medical Research Methodology, 10 (1). p. 17.
O'Donovan, G, Blazevich, AJ, Boreham, C, Cooper, AR, Crank, H, Ekelund, U, Fox, KR, Gately, P, Giles-Corti, B, Gill, JM, Hamer, M, McDermott, I, Murphy, M, Mutrie, N, Reily, JJ, Saxton, J and Stamatakis, E (2010) The ABC of Physical Activity for Health: a consensus statement from the British Association of Sport and Exercise Sciences. Journal of Sports Sciences, 28 (6). pp. 573-91.
Tew, GA, klonizakis, M and Saxton, JM (2010) Effects of ageing and fitness on skin-microvessel vasodilator function in humans. Eur J Appl Physiol, 109 (2). pp. 173-181.
Tew, Garry A., Klonizakis, Markos, Moss, James, Ruddock, Alan D., Saxton, John M and Hodges, Gary J. (2010) Role of sensory nerves in the rapid cutaneous vasodilator response to local heating in young and older endurance-trained and untrained men. Experimental Physiology, 96 (2). pp. 163-70. ISSN 09580670
klonizakis, M, Tew, GA, Michaels, J and Saxton, JM (2010) Effects of upper-limb exercise on lower-limb cutaneous microvascular function in post-surgical varicose-vein patients. Eur J Appl Physiol, 109 (6). pp. 1221-1224.
Hamer, M, Stamatakis, E and Saxton, JM (2009) The impact of physical activity on all-cause mortality in men and women after a cancer diagnosis. Cancer Causes and Control, 20 (2). pp. 225-231.
Tew, GA, Nawaz, S, Blagojevic, M, Zwierska, I and Saxton, JM (2009) Physiological predictors of maximum treadmill walking performance in patients with intermittent claudication. International Journal of Sports Medicine, 30 (6). pp. 467-472.
Tew, GA, Nawaz, S, Zwierska, I and Saxton, JM (2009) Limb-specific and cross-transfer effects of arm-crank exercise training in patients with symptomatic peripheral arterial disease. Clinical Science, 117 (12). pp. 405-413.
klonizakis, M, Tew, GA, Michaels, J and Saxton, JM (2009) Exercise training improves cutaneous microvascular endothelial function in post-surgical varicose vein patients. Microvascular Research, 78 (1). pp. 67-70.
klonizakis, M, Tew, GA, Michaels, J and Saxton, JM (2009) Impaired microvascular endothelial function is restored by acute lower-limb exercise in post-surgical varicose vein patients. Microvascular Research, 77 (2). pp. 158-162.
Oakley, C, Zwierska, I, Tew, GA, Beard, J and Saxton, JM (2008) Nordic poles immediately improve walking distance in patients with intermittent claudication. European Journal of Vascular and Endovascular Surgery, 36 (6). pp. 689-694.
Saxton, JM, Zwierska, I, Hopkinson, K, Espigares, E, Choksy, S, Nawaz, S, Walker, R and Pockley, AG (2008) Effect of upper- and lower-limb exercise training on circulating soluble adhesion molecules, hs-CRP and stress proteins in patients with intermittent claudication. European Journal of Vascular and Endovascular Surgery, 35 (5). pp. 607-613.
Daley, AJ, Crank, K, Mutrie, N, Saxton, JM and Coleman, R (2007) Patient recruitment into a randomised controlled trial of supervised exercise therapy in sedentary women treated for breast cancer. Contemporary Clinical Trials, 28 (5). pp. 603-613.
Daley, AJ, Crank, K, Mutrie, N, Saxton, JM and Coleman, R (2007) Determinants of adherence to exercise in women treated for breast cancer. European Journal of Oncology Nursing, 11. pp. 392-399.
Daley, AJ, Crank, K, Saxton, JM, Mutrie, N, Coleman, R and Roalfe, A (2007) Randomized trial of exercise therapy in women treated for breast cancer. Journal of Clinical Oncology, 25 (13). pp. 1713-1721.
Hodgson, SA, Mawson, SJ, Saxton, JM and Stanley, D (2007) Rehabilitation of two-part fractures of the neck of the humerus (two-year follow-up). Journal of Shoulder and Elbow Surgery, 16 (2). pp. 143-145.
Hopkinson, K, Williams, EA, Fairburn, B, Forster, S, Flower, DJ, Saxton, JM and Pockley, AG (2007) A Mito Tracker Green-based flow cytometric assay for natural killer cell activity: variability, the influence of platelets and a comparison of analytical approaches. Experimental Hematology, 35 (3). pp. 350-357.
Spencer, A, Covey, J, Saxton, JM and Loomes, G (2007) Are Some Deaths Worse Than Others? The Effect of 'Labelling' on People's Perceptions. University of London Working Papers, 620. pp. 1-32.
Saxton, JM, Daley, A, Woodroofe, N, Coleman, R, Powers, H, Mutrie, N, Siddall, V and Crank, H (2006) Study protocol to investigate the effect of a lifestyle intervention on body weight, psychological health status and risk factors associated with disease recurrence in women recovering from breast cancer treatment (ISRCTN08045231). Biomedical Central Cancer, 9 (6). p. 35.
Zwierska, I, Walker, RD, Choksy, SA, Male, JS, Pockley, AG and Saxton, JM (2006) Relative tolerance to upper- and lower-limb aerobic exercise in patients with peripheral arterial disease. European Journal of Vascular and Endovascular Surgery, 31 (2). pp. 157-163.
Zwierska, I, Walker, RD, Choksy, SA, Male, JS, Pockley, AG and Saxton, JM (2005) Upper- versus lower-limb aerobic exercise rehabilitation in patients with symptomatic peripheral arterial disease: a randomized controlled trial. Journal of Vascular Surgery, 42 (6). pp. 1122-1130.
Daley, AJ, Mutrie, N, Crank, H, Coleman, R and Saxton, JM (2004) Exercise therapy inwomen who have had breast cancer: design of the Sheffield women's exercise and well-being project. Health Education Research, 19 (6). pp. 686-697.
Zwierska, I, Nawaz, S, Walker, RD, Wood, RF, Pockley, AG and Saxton, JM (2004) Treadmill versus shuttle walk tests of walking ability in intermittent claudication. Medicine and Science in Sports and Exercise, 36 (11). pp. 1835-1840.
Mason, HJ, Poole, K and Saxton, JM (2003) A critique of a UK standardized test of finger rewarming after cold provocation in the diagnosis and staging of hand-arm vibration syndrome. Occupational Medicine, 53 (5). pp. 325-330.
Saxton, JM, Claxton, D, Winter, E and Pockley, AG (2003) Peripheral blood leucocyte functional responses to acute eccentric exercise in humans are influenced by systemic stress, but not by exercise-induced muscle damage. Clinical Science, 104 (1). pp. 69-77.
Nawaz, S, Walker, RD, Wilkinson, CH, Saxton, JM, Pockley, AG and Wood, RFM (2001) The inflammatory response to upper and lower limb exercise and the effects of exercise training in individuals with claudication. Journal of Vascular Surgery, 33 (2). pp. 392-400.
Hole, CD, Smith, GH, Hammond, J, Kumar, A, Saxton, JM and Cochrane, T (2000) Dynamic control and conventional strength ratios of the quadriceps and hamstrings in subjects with anterior cruciate ligament deficiency. Ergonomics, 43 (10). pp. 1603-1609.
Saxton, JM (2000) A review of current literature on physiological tests and soft tissue bomarkers applicable to work-related upper limb disorders. Occupational Medicine, 50. pp. 121-130.
Walker, RD, Nawaz, S, Wilkinson, CH, Saxton, JM, Pockley, AG and Wood, RFM (2000) Influence of upper amd lower limb exercise training on cardiovascular funtion and walking distances in patients with intermittent claudication. Journal of Vascular Surgery, 31 (4). pp. 662-669.
Child, R, Brown, S, Day, S, Donnelly, A, Roper, H and Saxton, JM (1999) Changes in indices of antioxidant status, lipid peroxidation and inflammation in human skeletal muscle after eccentric muscle action. Clinical Science, 96 (1). pp. 105-115.
Child, R, Brown, SJ, Day, SH, Saxton, JM and Donnelly, A (1998) Manipulation of knee extensor force using percutaneous electrical myostimulation during eccentric muscle actions: Effects on indices of muscle damage in humans. International Journal of Sports Medicine, 19 (7). pp. 468-473.
Child, R, Saxton, JM and Donnelly, A (1998) Comparison of eccentric knee extensor muscle actions at two different lengths on indices of damage and angle-specific torque production in humans. Journal of Sports Sciences, 16 (4). pp. 301-308.
Saxton, JM and Pockley, AG (1998) Effect of ex vivo stirage on human peripheral blood neutrophil expression of CD11b and the stabilizing effects of Cyto-Chex. Journal of Immunological Methods, 214 (1-2). pp. 11-17.
Brown, SJ, Child, R, Donnelly, A, Saxton, JM and Day, SH (1996) Changes in human skeletal muscle contractile function following stimulated eccentric exercise. European Journal of Applied Physiology, 72 (5-6). pp. 515-521.
Saxton, JM and Donnelly, A (1996) Length-specific impairment of skeletal muscle contractile function after eccentric muscle actions in man. Clinical Science, 90. pp. 119-125.
Saxton, JM, Clarkson, J, James, R, Miles, M, Westerfer, M, Clark, S and Donnelly, A (1995) Neuromuscular dysfunction following maximum voluntary eccentric exercise. Medicine and Science in Sports and Exercise, 27. pp. 1185-1193.
Saxton, JM and Donnelly, A (1995) Light concentric exercise during recovery from exercise-induced muscle damage. International Journal of Sports Medicine, 16 (6). pp. 347-351.
Saxton, JM, Donnelly, A and Roper, HP (1994) Indices of free radical mediated damage after maximum voluntary eccentric and concentric muscular work. European Journal of Applied Physiology, 68 (3). pp. 189-193.
External Activities and Indicators of Esteem
- BASES Accredited Research Physiologist and Honorary Fellow of BASES (FBASES)
- Member of the BASES Accreditation Committee (2007– present)
- Council Member of the Society for Research in Rehabilitation (2009 – 2012)
- Editorial Board member for the Physician and Sportsmedicine (2008 – present)
- Member of the Editorial Advisory Board for Clinical Science (2010 – present)
Professional Activities
- Member of British Association of Sport and Exercise Science (BASES)
- Member of Physiological Society
- Member of Society for Research in Rehabilitation
Administrative Posts/Responsibilities
- Associate Dean for Enterprise and Engagement, Faculty of Medicine and Health Sciences, UEA (2010-2012).
- Director of Learning and Teaching Quality (Postgraduate Research), School of Allied Health Professions, UEA (2011- present).
